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Antidepressants associated with significantly elevated risk of death, researchers find

It's widely known that brain serotonin affects mood, and that most commonly used antidepressant treatment for depression blocks the absorption of serotonin by neurons. It is less widely known, though, that all the major organs of the body -- the heart, kidneys, lungs, liver -- use serotonin from the bloodstream. Antidepressants block the absorption of serotonin in these organs as well, and the researchers warn that antidepressants could increase the risk of death by preventing multiple organs from functioning properly. The researchers reviewed studies involving hundreds of thousands of people and found that antidepressant users had a 33% higher chance of death than non-users. Antidepressant users also had a 14% higher risk of cardiovascular events, such as strokes and heart attacks. The findings were published in the journal  Psychotherapy and Psychosomatics . "We are very concerned by these results. They suggest that we shouldn't be taking antidepressant drugs w...

Chimera viruses can help the fight against lymphomas

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These are mice spleen cells (blue) contaminated with the chimera kaposi virus displaying the LANA protein (purple). Credit score: Pedro Simas Lab, iMM Lisboa Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that enables the examine of molecules to deal with cancers attributable to human herpes virus an infection in mice fashions of illness. There are a number of sorts of herpesvirus in a position to infect people, resembling herpes simplex, chickenpox, cytomegalovirus , Epstein-Barr and Kaposi Sarcoma herpesvirus. One of many important traits of herpesviruses is their capacity to contaminate their hosts for all times and in a small share of those individuals in the end result in most cancers. Cancers related to Kaposi virus an infection have an Achilles heel: their cells' viability is immediately depending on the survival of the virus, which signifies that if the virus have been to be eradicated most cancers ce...